"Coping with the cold"- Octopus & RNA editing
It is interesting to know how octopuses 🐙 and squid adapt to cold temperatures by altering their molecular makeup. When subjected to a 10-degree Celsius drop in water temperature, California two-spot octopuses and California market squid exhibited significant changes in the proteins they produced by editing their RNA. RNA editing is a process where messenger RNA (mRNA) is modified, which can affect protein behaviour and production. While humans and other organisms have some capacity for RNA editing, cephalopods take it to extreme levels, modifying thousands of mRNA sites. Researchers conducted experiments by adjusting the temperature of the tanks housing the cephalopods. They found that cool temperatures triggered substantial RNA editing, altering about a third of the protein production instructions. The editing occurred rapidly within a few hours and primarily affected the nervous system. The changes in mRNA editing resulted in modified behaviour at the molecular lev...